Casework Genetics "Resolving DNA Mixtures in Forensic Identification" Casework Genetics
 

AAFS 2011, Chicago         

Dr. Kevin McElfresh will be presenting "Utilizing High Density SNP Array Mixtures: An Operational Assessment" at the 63rd Annual Meeting of the American Academy of Forensic Sciences. If you're attending the conference, we hope to see you there.
                  LOCATION: Hyatt Regency Chicago
                  PROGRAM: Criminalistics Section
                  DATE/TIME: Friday February 25, 2011 / 10:55am - 11:20am

Click here to download the full presentation abstract.

AAFS Conference Image
San Antonio Promega

          ISHI 2010, San antonio

The Casework Genetics Team flew to San Antonio for their second Promega Conference. Thank you to everyone who stopped by our booth at ISHI 21 – it was great to see you in San Antonio and we can’t wait to see you at National Harbor next year!

 
 

March 2010         
Casework Genetics SNP Symposium         
Woodbridge, VA         

The 1st SNP Symposium was held March 22 – 24 for experienced analysts who are actively engaged in or strongly considering the implementation of SNP technology.  Speakers included our own Dr. McElfresh & Dr. Sosnowski and Dr. George Duncan from the Broward County Sherriff’s Office.  Adam Lowe and Edward Sawicki from Illumina both made presentations.  In addition, James Frost from BioTX made a special presentation of his automation solutions for forensic technology.  Thank you to all who joined us; the conference was a great success and we look forward to many more in the years to come.

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SNP Symposium Presentation

 

CG in Vegas

CG in Vegas

          ISHI 2009, Las Vegas

Dr. Kevin McElfresh delivered a presentation at the 20th International Symposium on Human Identification “The Real Deal” sponsored by Promega held in Las Vegas, Nevada October 12-15, 2009.

Abstract: In 20 years the amount of DNA required for a DNA test has decreased from micrograms to nanograms, the time required has decreased from weeks to hours, and the acceptance of the technology from skeptical to fundamental. However one of the remaining persistent problems is the interpretation of mixtures, that is, multiple individuals within a single sample. We show that by applying GWAs based analysis methods to forensic samples it is possible to resolve individuals within complex mixtures, as well as address other challenging forensic sample types such as in highly degraded samples. Our technology utilizes the cumulative statistical power from genotyping hundreds of thousands of SNPs to analyze single source forensic samples as well as complex mixtures. The data show that it is possible to parse a mixture of a few individuals using as few as several thousand SNPs and mixtures of hundreds of individuals using 300,000 or more SNPs.

Work presented is proprietary and patent pending.

See Dr. Kevin McElfresh's Presentation "Utilizing 300,000 or More Single Nucleotide Polymorphisms
for the Identification of Individuals Within a Forensic Mixture" here.

 
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